An Observation of a Very High Swelling of Bromovirus Members at Specific Ionic Strengths and pH.

ABSTRACT: Cowpea chlorotic mottle virus (CCMV) and brome mosaic virus (BMV) are naked plant viruses with similar characteristics; both form a T = 3 icosahedral protein capsid and are members of the bromoviridae family. It is well known that these viruses completely disassemble and liberate their genome at a pH around 7.2 and 1 M ionic strength. However, the 1 M ionic strength condition is not present inside cells, so an important question is how these viruses deliver their genome inside cells for their viral replication. There are some studies reporting the swelling of the CCMV virus using different techniques. For example, it is reported that at a pH~7.2 and low ionic strength, the swelling observed is about 10% of the initial diameter of the virus. Furthermore, different regio

SUBMITTER: Segovia-Gonzalez XF 

PROVIDER: S-EPMC10612077 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature