Efficacy of IVIG therapy for patients with sepsis: a systematic review and meta-analysis.

ABSTRACT:

Background

Sepsis is an overwhelming reaction to infection that comes with high morbidity and mortality. It requires urgent interventions in order to improve outcomes. Intravenous immunoglobulins (IVIG) are considered as potential therapy in sepsis patients. Results of trials on IVIG as adjunctive therapy for sepsis have been conflicting due to the variability in population characteristics, country geography and drug dosage form in different studies.

Methods

A systematic article search was performed for eligible studies published up to January, 31, 2023, through the PubMed, Embase, Cochrane Library and Chinese National Knowledge Infrastructure database. The included articles were screened by using rigorous inclusion and exclusion criteria. Subgroup analyses were conducted ac

SUBMITTER: Pan B 

PROVIDER: S-EPMC10612304 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature