Serial assessments of cardiac output and mixed venous oxygen saturation in comatose patients after out-of-hospital cardiac arrest.

ABSTRACT:

Aim

To assess the association with outcomes of cardiac index (CI) and mixed venous oxygen saturation (SvO2) in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA).

Methods

In the cohort study of 789 patients included in the "BOX"-trial, 565 (77%) patients were included in this hemodynamic substudy (age 62 ± 13 years, male sex 81%). Pulmonary artery catheters were inserted shortly after ICU admission. CI and SvO2 were measured as soon as possible in the ICU and until awakening or death. The endpoints were all-cause mortality at 1 year and renal failure defined as need for renal replacement therapy.

Results

First measured CI was median 1.7 (1.4-2.1) l/min/m², and first measured SvO2 was median 67 (61-73) %. CI < median with SvO2 > median

SUBMITTER: Grand J 

PROVIDER: S-EPMC10612339 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature