Effect of flow rate ratio and positioning on a lighthouse tip ECMO return cannula.

ABSTRACT: Extracorporeal membrane oxygenation is a life-saving support therapy in the case of cardiopulmonary refractory failure. Its use is associated to complications due to the presence of artificial surfaces and supraphysiological stress conditions. Thus, knowledge of the fluid structures associated to each component can give insight into sources of blood damage. In this study, an experimentally validated numerical study of a conventional lighthouse tip cannula in return configuration was carried out to characterize the flow structures using water or a Newtonian blood analog with different flow rate ratios and cannula positioning and their influence on hemolysis. The results showed that strong shear layers developed where the jets from the side holes met the co-flow. Stationary backflow regions

SUBMITTER: Fiusco F 

PROVIDER: S-EPMC10613146 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature