Effect of restrictive cumulative fluid balance on 28-day survival in invasively ventilated patients with moderate to severe ARDS due to COVID-19.

ABSTRACT: This study aimed to evaluate the effect of two restrictive cumulative fluid balance (CFB) trends on survival and on major clinical outcomes in invasively ventilated patients with moderate to severe respiratory distress syndrome (ARDS) due to SARS-CoV-2. Prospective data collection was conducted on patients in the intensive care unit (ICU) originating from a tertiary university hospital. The primary outcomes were the risk association between the CFB trend during D₀ to D₇ and 28-day survival. The secondary outcomes were ICU mortality, in-hospital mortality, the need for invasive ventilation at D₂₈, administration of vasoactive drugs at D₇, time on invasive ventilation after D₇, and length of ICU and hospital stay. 171 patients were enrol

SUBMITTER: Esper Treml R 

PROVIDER: S-EPMC10613222 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature