Prognostic models predicting transition to psychotic disorder using blood-based biomarkers: a systematic review and critical appraisal.

ABSTRACT: Accumulating evidence suggests individuals with psychotic disorder show abnormalities in metabolic and inflammatory processes. Recently, several studies have employed blood-based predictors in models predicting transition to psychotic disorder in risk-enriched populations. A systematic review of the performance and methodology of prognostic models using blood-based biomarkers in the prediction of psychotic disorder from risk-enriched populations is warranted. Databases (PubMed, EMBASE and PsycINFO) were searched for eligible texts from 1998 to 15/05/2023, which detailed model development or validation studies. The checklist for Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies (CHARMS) was used to guide data extraction from eligible texts and the

SUBMITTER: Byrne JF 

PROVIDER: S-EPMC10613280 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature