Systematic Analysis of the Literature in Search of Defining Systemic Sclerosis Subsets.

ABSTRACT:

Objective

Systemic sclerosis (SSc) is a multisystem disease with heterogeneity in presentation and prognosis.An international collaboration to develop new SSc subset criteria is underway. Our objectives were to identify systems of SSc subset classification and synthesize novel concepts to inform development of new criteria.

Methods

Medline, Cochrane MEDLINE, the Cumulative Index to Nursing and Allied Health Literature, EMBASE, and Web of Science were searched from their inceptions to December 2019 for studies related to SSc subclassification, limited to humans and without language or sample size restrictions.

Results

Of 5686 citations, 102 studies reported original data on SSc subsets. Subset classification systems relied on extent of skin involvement and/or SSc-speci

SUBMITTER: Nevskaya T 

PROVIDER: S-EPMC10613330 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature