Association between serum ferritin and uric acid levels and nonalcoholic fatty liver disease in the Chinese population.

ABSTRACT:

Background

The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Accumulating evidence suggests that serum ferritin and uric acid (UA) are strongly associated with the risk of NAFLD, but no consensus has been reached.

Objective

We sought to demonstrate the association between serum ferritin, UA levels, and NAFLD risk in a large cohort study.

Methods

We separated 2,049 patients into non-NAFLD and NAFLD groups. The NAFLD group had four subgroups based on serum ferritin and four subgroups based on UA quartile levels. We used binary logistic regression to evaluate the correlation between serum ferritin, UA, and NAFLD. Additionally, an area under the curve (AUC) of receiver operating characteristic analysis (ROC) was used to predict the diagno

SUBMITTER: Zhou F 

PROVIDER: S-EPMC10613435 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature