Uncovering neural pathways underlying bulimia nervosa: resting-state neural connectivity disruptions correlate with maladaptive eating behaviors.

ABSTRACT:

Purpose

Bulimia nervosa (BN) is characterized by recurrent binge-eating episodes and inappropriate compensatory behaviors. This study investigated alterations in resting-state surface-based neural activity in BN patients and explored correlations between brain activity and eating behavior.

Methods

A total of 26 BN patients and 28 healthy controls were enrolled. Indirect measurement of cerebral cortical activity and functional connectivity (FC) analyses were performed in Surfstat. A principal component analysis (PCA) model was used to capture the commonalities within the behavioral questionnaires from the BN group.

Results

Compared with the healthy control group, the BN group showed decreased surface-based two-dimensional regional homogeneity in the right superior pari

SUBMITTER: Wang JN 

PROVIDER: S-EPMC10613592 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature