Prognostic significance of the systemic immune-inflammation index in patients with extranodal natural killer/T-cell lymphoma.

ABSTRACT:

Background

The systemic immune-inflammation index (SII) is based on the neutrophil, platelet, and lymphocyte counts, and has been identified as a prognostic marker in multiple types of cancer. However, the potential value of the SII for predicting survival outcomes in patients with extranodal natural killer/T-cell lymphoma (ENKTCL) has not been investigated thus far.

Method

This study included 382 patients with ENKTCL treated with asparaginase-base regimens from 2021 to 2017 in West China Hospital (Chengdu, China). Clinical and demographic variables, as well as the prognostic value of the SII, were analyzed using Cox proportional hazards regression analysis.

Results

The complete and objective response rates were 55.8% and 74.9%, respectively. Patients with high SII we

SUBMITTER: Hai T 

PROVIDER: S-EPMC10613892 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature