Ostreid herpesvirus 1 latent infection and reactivation in adult Pacific oysters, Crassostrea gigas.

ABSTRACT: Ostreid herpesvirus 1 (OsHV-1) is one of the most economically important pathogens of Pacific oysters. Understanding the pathogenesis of this virus is critical to developing tools to control outbreaks on shellfish farms. OsHV-1 is genetically related to vertebrate herpesviruses, which have a lytic and a latent stage, with the latent stage capable of being reactivated to the lytic stage. Here, OsHV-1 latency in Pacific oysters was investigated in experimentally and naturally infected oysters. Lytic infection in one-year-old oysters injected with the Tomales Bay strain of OsHV-1 was detectable between 1 and 4 days post-injection (dpi) but was not detectable after 5 dpi. The injected oysters shed 1 × 10² to 1 × 10⁴ DNA copies/ml into the water during the 4-day acute phas

SUBMITTER: Divilov K 

PROVIDER: S-EPMC10613911 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature