Clinical characteristics and risk factors of Helicobacter pylori infection-associated Sjogren's syndrome.

ABSTRACT:

Objective

Although infectious pathogens are predominant factors for inducing and maintaining immune system disorders, there exist few reports establishing the significant correlation between Helicobacter pylori (H. pylori) infection and Sjogren's syndrome. This study aims to demonstrate the correlation between Sjogren's syndrome and H. pylori infection in patients, highlighting various clinical characteristics and risk factors.

Methods

A single-center retrospective observational study was conducted in patients (n = 224) admitted from January 1, 2012, to February 10, 2021, in the First Affiliated Hospital of Wenzhou Medical University (Wenzhou, China). All the recruited subjects with Sjogren's syndrome and H. pylori infection were only included by validating the available med

SUBMITTER: He Y 

PROVIDER: S-EPMC10614117 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature