Optimizing the first-line treatment for metastatic colorectal cancer.

ABSTRACT: Colorectal cancer represents an important oncological challenge both for its incidence, which makes it an important health problem, and for its biological complexity, which has made clinical results very difficult in terms of outcome for this category of patients. To date these diseases should not be treated as a single entity but it is necessary to distinguish colorectal cancers based on characteristics that nowadays are essential to have greater therapeutic benefits. These include the sideness of the disease, the state of microsatellites, the presence of prognostic and predictive mutations of response to treatments currently available in clinical practice, which are associated with new therapeutic targets. The greatest challenge in the future will be to circumvent the resistance mechanis

SUBMITTER: Cherri S 

PROVIDER: S-EPMC10614157 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature