Heart Rate Characteristics Monitoring for Late-Onset Sepsis in Preterm Infants: A Systematic Review.

ABSTRACT:

Background

Early diagnosis of late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) by monitoring heart rate characteristics (HRC) of preterm infants might reduce the risk of death and morbidities. We aimed to systematically assess the effects of HRC monitoring on death, LOS, and NEC.

Methods

A systematic search was performed in MEDLINE, Embase, Cochrane Library, and Web of Science.

Results

Fifteen papers were included in this review. Three of these papers reported results from the only identified randomized controlled trial (RCT). This RCT showed that HRC monitoring resulted in a small but significant reduction in mortality (absolute risk reduction 2.1% [95% confidence interval 0.01-4.14]) without any differences in neurodevelopmental impairment. The risk of bi

SUBMITTER: Koppens HJ 

PROVIDER: S-EPMC10614451 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature