Refining a Multifaceted Model of Perceived Utility of Genomic Sequencing Results.

ABSTRACT:

Introduction

Research on the perceived utility of genomic sequencing has focused primarily on pediatric populations and on individuals and families with rare genetic diseases. Here, we evaluate how well a multifaceted perceived utility model developed with these populations applies to a diverse, adult population aged 18-49 at risk for hereditary cancer and propose new considerations for the model.

Methods

Participants received clinical genomic sequencing in the Cancer Health Assessments Reaching Many (CHARM) study. Semi-structured qualitative interviews were conducted with a subset of participants at 1 and 6 months after results disclosure. We used an approach influenced by grounded theory to examine perceptions of the utility of genomic sequencing and analyzed how utility i

SUBMITTER: Duenas DM 

PROVIDER: S-EPMC10614499 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature