Theranostics with photodynamic therapy for personalized medicine: to see and to treat.

ABSTRACT: Photodynamic Therapy (PDT) is an approved treatment modality, which is presently receiving great attention due to its limited invasiveness, high selectivity and limited susceptibility to drug resistance. Another related research area currently expanding rapidly is the development of novel theranostic agents based on the combination of PDT with different imaging technologies, which allows for both therapy and diagnosis. This combination can help to address issues of suboptimal biodistribution and selectivity through regional imaging, while therapeutic agents enable an effective and personalized therapy. In this review, we describe compounds, whose structures combine PDT photosensitizers with different imaging probes - including examples for near-infrared optical imaging, magnetic resonance

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10614685 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature