Ontology highlight
ABSTRACT:
SUBMITTER: Zhao Z
PROVIDER: S-EPMC10614717 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Zhao Zhenyu Z Wei Zhen Z Zheng Jiaxin J Li Zhihong Z Zou Hecun H Wen Xiang X Li Fahong F Wang Xueyu X Huang Qian Q Zeng Huaqing H Fan Hui H Cai Xuefei X Zhang Jiming J Jia Bei B Huang Ailong A Lu Mengji M Lin Yong Y
Emerging microbes & infections 20231026 2
Chronic hepatitis B virus (HBV) infection remains one of the major global public health concerns, and it develop into liver fibrosis, cirrhosis, and hepatocellular carcinoma. Recent evidence suggests that endosomal and autophagic vesicles are beneficial for HBV replication. However, it has not been well elucidated how HBV exploits such intracellular vesicle systems for its replication. RAB5A, a member of small GTPase family, plays crucial roles in early endosome biogenesis and autophagy initiati ...[more]