Diurnal fluctuations in steroid hormones tied to variation in intrinsic functional connectivity in a densely sampled male.

ABSTRACT: Most of mammalian physiology is under the control of biological rhythms, including the endocrine system with time-varying hormone secretion. Precision neuroimaging studies provide unique insights into the means through which our endocrine system regulates dynamic properties of the human brain. Recently, we established estrogen's ability to drive widespread patterns of connectivity and enhance the functional efficiency of large-scale brain networks in a woman sampled every 24h across 30 consecutive days, capturing a complete menstrual cycle. Steroid hormone production also follows a pronounced sinusoidal pattern, with a peak in testosterone between 6-7am and nadir between 7-8pm. To capture the brain's response to diurnal changes in hormone production, we carried out a companion precision im

SUBMITTER: Grotzinger H 

PROVIDER: S-EPMC10614853 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature