Environmental sampling for typhoidal Salmonellas in household and surface waters in Nepal identifies potential transmission pathways.

ABSTRACT:

Introduction

Salmonella Typhi and Salmonella Paratyphi, fecal-oral transmitted bacterium, have temporally and geographically heterogeneous pathways of transmission. Previous work in Kathmandu, Nepal implicated stone waterspouts as a dominant transmission pathway after 77% of samples tested positive for Salmonella Typhi and 70% for Salmonella Paratyphi. Due to a falling water table, these spouts no longer provide drinking water, but typhoid fever persists, and the question of the disease's dominant pathway of transmission remains unanswered.

Methods

We used environmental surveillance to detect Salmonella Typhi and Salmonella Paratyphi A DNA from potential sources of transmission. We collected 370, 1L drinking water samples from a population-based random sample of households i

SUBMITTER: LeBoa C 

PROVIDER: S-EPMC10615262 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature