Risk factors for proliferative vitreoretinopathy after retinal detachment surgery: A systematic review and meta-analysis.

ABSTRACT:

Background

To comprehensively investigate risk factors for proliferative vitreoretinopathy (PVR) after retinal detachment (RD) surgery.

Methods

PubMed, Embase, Cochrane Library, and Web of Science were systematically searched until May 22, 2023. Risk factors included demographic and disease-related risk factors. Odds ratios (ORs) and weighted mean differences (WMDs) were used as the effect sizes, and shown with 95% confidence intervals (CIs). Sensitivity analysis was conducted. The protocol was registered with PROSPERO (CRD42022378652).

Results

Twenty-two studies of 13,875 subjects were included in this systematic review and meta-analysis. Increased age was associated with a higher risk of postoperative PVR (pooled WMD = 3.98, 95%CI: 0.21, 7.75, P = 0.038). Smokers ha

SUBMITTER: Xiang J 

PROVIDER: S-EPMC10615281 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature