Contrasting modes of macro and microsynteny evolution in a eukaryotic subphylum.

ABSTRACT: Examination of the changes in order and arrangement of homologous genes is key for understanding the mechanisms of genome evolution in eukaryotes. Previous comparisons between eukaryotic genomes have revealed considerable conservation across species that diverged hundreds of millions of years ago (e.g., vertebrates,^1,2,3 bilaterian animals,^4,5 and filamentous fungi⁶). However, understanding how genome organization evolves within and between eukaryotic major lineages remains underexplored. We analyzed high-quality genomes of 120 representative budding yeast species (subphylum Saccharomycotina) spanning ∼400 million years of eukaryotic evolution to examine how their genome organization evolved

SUBMITTER: Li Y 

PROVIDER: S-EPMC10615371 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature