Antibody response and soluble mediator profile in the first six months following acute SARS-CoV-2 infection.

ABSTRACT: The COVID-19 pandemic has caused a severe global health and economic crisis, with significant consequences for human mortality and morbidity. Therefore, there is an urgent need for more studies on the immune response to SARS-CoV-2 infection, both to enhance its effectiveness and prevent its deleterious effects. This study presents the chronology of antibodies during six months after infection in hospitalized patients and the kinetics of serum soluble mediators of the cellular response triggered by SARS-CoV-2. Samples and clinical data from 330 patients hospitalized at the Hospital da Baleia in Belo Horizonte, Brazil, who were suspected of having COVID-19, were collected at the time of hospitalization and during 6 months after infection. The immune response was analyzed by enzyme-linked imm

SUBMITTER: Corsini CA 

PROVIDER: S-EPMC10616118 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature