FMRI fluctuations within the language network are correlated with severity of hallucinatory symptoms in schizophrenia.

ABSTRACT: Although schizophrenia (SZ) represents a complex multiform psychiatric disorder, one of its most striking symptoms are auditory verbal hallucinations (AVH). While the neurophysiological origin of this pervasive symptom has been extensively studied, there is so far no consensus conclusion on the neural correlates of the vulnerability to hallucinate. With a network-based fMRI approach, following the hypothesis of altered hemispheric dominance (Crow, 1997), we expected that LN alterations might result in self-other distinction impairments in SZ patients, and lead to the distressing subjective experiences of hearing voices. We used the independent component analysis of resting-state fMRI data, to first analyze LN connectivity in three groups of participants: SZ patients with and without halluc

SUBMITTER: Spironelli C 

PROVIDER: S-EPMC10616281 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature