The effect of biologics in lung function and quality of life of patients with united airways disease: A systematic review.

ABSTRACT:

Background

Increasing evidence supports the united airway disease concept for the management of upper and lower respiratory tract diseases, particularly in patients with asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). However, evidence for a combined approach in asthma and CRSwNP is scarce.

Objective

In this systematic review, we focused on the role of biologics in the lung function and quality of life in patients with severe asthma and CRSwNP.

Methods

We conducted a systematic search of 3 electronic databases using 2 search strategies to identify studies published from January 2010 to March 2022. Quality assessment was performed with the Critical Appraisal Skills Programme.

Results

Of 1030 studies identified, 48 original studies reporting data of

SUBMITTER: Dominguez-Ortega J 

PROVIDER: S-EPMC10616425 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature