Effects of oral nutritional supplements on the nutritional status and inflammatory markers in patients on maintenance dialysis: a systematic review and meta-analysis of randomized clinical trials.

ABSTRACT:

Background and aims

Patients on hemodialysis (HD) or peritoneal dialysis (PD) often have insufficient energy and protein intake, resulting in poor nutritional status and adverse outcomes. Oral nutritional supplements (ONSs) are the most commonly used to increase such patients' energy and protein intakes.

Methods

In this systematic review and meta-analysis, we analyzed studies on nutritional status, inflammatory markers, and electrolyte levels in patients on dialysis receiving ONSs. We searched four electronic databases from inception until 31 December 2022, for randomized controlled trials comparing ONS treatment versus placebo or routine care.

Results

22 studies with 1185 patients on dialysis were included in our meta-analysis. Compared with the control group, the ON

SUBMITTER: Liu PJ 

PROVIDER: S-EPMC10616451 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature