Use of a taurolidine containing antimicrobial wash to reduce cardiac implantable electronic device infection.

ABSTRACT:

Aims

TauroPace (Tauropharm, Bavaria Germany), a taurolidine solution for combating cardiac implantable electronic device (CIED) infection, was compared with a historical control of 3% hydrogen peroxide (H2O2) in a prospective observational study.

Methods and results

The device pocket was irrigated, and all hardware accessible within (leads, suture sleeves, pulse generator) was wiped with H2O2, TauroPace, or taurolidine in a galenic formulation during any invasive CIED procedure at the study centre. Only CIED procedures covered by TauroPace or H2O2 from 1 January 2017 to 28 February 2022 were included for analysis. Patients who underwent >1 procedure were censored for the last treatment group and reassigned at the next procedure. The primary endpoint was major CIED infection

SUBMITTER: Borov S 

PROVIDER: S-EPMC10616572 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature