Kidney Biopsy Findings and Clinical Outcomes of US Veterans with Inflammatory Bowel Disease.

ABSTRACT:

Introduction

Patients with inflammatory bowel disease (IBD; ulcerative colitis [UC] and Crohn's disease [CD]) may have unique patterns of kidney injury related to their underlying or coexisting disease or to medications. We present the kidney biopsy findings and clinical outcomes of veterans with UC or CD from the US Department of Veteran's Affairs (VA) health system.

Methods

Histopathologic and clinical data were extracted by retrospective review of the VA electronic health record of patients with IBD and a kidney biopsy between 2000 and 2018. Incident end-stage kidney disease (ESKD) was defined as requirement of kidney replacement therapy. Statistical analyses were performed using SAS.

Results

A total of 140 patients (UC: 91 and CD: 49) underwent kidney biopsy. The

SUBMITTER: Ravipati P 

PROVIDER: S-EPMC10616669 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature