Gut microbiota in adults with moyamoya disease: characteristics and biomarker identification.

ABSTRACT:

Background and purpose

When it comes to the onset of moyamoya disease (MMD), environmental variables are crucial. Furthermore, there is confusion about the relationship between the gut microbiome, an environmental variable, and MMD. Consequently, to identify the particular bacteria that cause MMD, we examined the gut microbiome of MMD individuals and healthy controls (HC).

Methods

A prospective case-control investigation was performed from June 2021 to May 2022. The fecal samples of patients with MMD and HC were obtained. Typically, 16S rRNA sequencing was employed to examine their gut microbiota. The QIIME and R softwares were used to examine the data. The linear discriminant analysis effect size analysis was used to determine biomarkers. Multivariate analysis by linear mod

SUBMITTER: Yu X 

PROVIDER: S-EPMC10616959 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature