Do alternative tobacco products induce less adverse respiratory risk than cigarettes?

ABSTRACT:

Rationale

Due to the relatively short existence of alternative tobacco products, gaps exist in our current understanding of their long-term respiratory health effects. We therefore undertook the first-ever side-by-side comparison of the impact of chronic inhalation of aerosols emitted from electronic cigarettes (EC) and heated tobacco products (HTP), and combustible cigarettes (CC) smoke.

Objectives

To evaluate the potential differential effects of alternative tobacco products on lung inflammatory responses and efficacy of vaccination in comparison to CC.

Methods

Mice were exposed to emissions from EC, HTP, CC, or air for 8 weeks. BAL and lung tissue were analyzed for markers of inflammation, lung damage, and oxidative stress. Another group was exposed for 12 weeks an

SUBMITTER: Bhat TA 

PROVIDER: S-EPMC10617138 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature