The association of upper airway anatomy with cognitive test performance: the Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Background

Numerous upper airway anatomy characteristics are risk factors for sleep apnea, which affects 26% of older Americans, and more severe sleep apnea is associated with cognitive impairment. This study explores the pathophysiology and links between upper airway anatomy, sleep, and cognition.

Methods

Participants in the Multi-Ethnic Study of Atherosclerosis underwent an upper airway MRI, polysomnography to assess sleep measures including the apnea-hypopnea index (AHI) and completed the Cognitive Abilities Screening Instrument (CASI). Two model selection techniques selected from among 67 upper airway measures those that are most strongly associated with CASI score. The associations of selected upper airway measures with AHI, AHI with CASI score, and selected upper airwa

SUBMITTER: Nance RM 

PROVIDER: S-EPMC10617161 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature