Utilization of spontaneous breathing trial, objective cough test, and diaphragmatic ultrasound results to predict extubation success: COBRE-US trial.

ABSTRACT:

Background

The results of clinical and weaning readiness tests and the spontaneous breathing trial (SBT) are used to predict the success of the weaning process and extubation.

Methods

We evaluated the capacity of the cuff leak test, rate of rapid and shallow breathing, cough intensity, and diaphragmatic contraction velocity (DCV) to predict the success of the SBT and extubation in a prospective, multicenter observational study with consecutive adult patients admitted to four intensive care units. We used receiver operating characteristic (ROC) curves to assess the tests' predictive capacity and built predictive models using logistic regression.

Results

We recruited 367 subjects who were receiving invasive mechanical ventilation and on whom 456 SBTs were performed, wit

SUBMITTER: Varon-Vega F 

PROVIDER: S-EPMC10617213 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature