Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potential.

ABSTRACT:

Background

Cells have been increasingly known to release extracellular vesicles (EVs) to the extracellular environment under physiological and pathological conditions. A plethora of studies have revealed that EVs contain cell-derived biomolecules and are found in circulation, thereby implicating them in molecular trafficking between cells. Furthermore, EVs have an effect on physiological function and disease development and serve as disease biomarkers.

Main body

Given the close association  between EV circulation and vascular disease, this review aims to provide a brief introduction to EVs, with a specific focus on the EV cargoes participating in pathological mechanisms, diagnosis, engineering, and clinical potential, to highlight the emerging evidence suggesting promising t

SUBMITTER: Liu W 

PROVIDER: S-EPMC10617214 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature