Prokinetics for the treatment of functional dyspepsia: an updated systematic review and network meta-analysis.

ABSTRACT:

Background

Since the previous network meta-analysis assessing the efficacy of prokinetics for functional dyspepsia (FD), there have been a number of new studies and cinitapride is a new prokinetic agent for FD. This updated meta-analysis aimed to explore the efficacy and safety of prokinetics for FD.

Methods

An updated study search in Pubmed, EMBASE, Cochrane Library and Web of Science was conducted in literatures published from July 2015 to March 2023. Randomized controlled trials investigating the use of prokinetics in adult FD patients were included. The primary outcome was the total efficacy rate and the secondary outcome was adverse events. A Bayesian network meta-analysis was performed using R software.

Results

A total of 28 studies were included. Network meta-a

SUBMITTER: Qi Q 

PROVIDER: S-EPMC10617220 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature