Joint association of sedentary behavior and vitamin D status with mortality among cancer survivors.

ABSTRACT:

Background

Sedentary behavior and vitamin D deficiency are independent risk factors for mortality in cancer survivors, but their joint association with mortality has not been investigated.

Methods

We analyzed data from 2914 cancer survivors who participated in the National Health and Nutrition Examination Survey (2007-2018) and followed up with them until December 31, 2019. Sedentary behavior was assessed by self-reported daily hours of sitting, and vitamin D status was measured by serum total 25-hydroxyvitamin D (25(OH)D) levels.

Results

Among 2914 cancer survivors, vitamin D deficiency was more prevalent in those with prolonged daily sitting time. During up to 13.2 years (median, 5.6 years) of follow-up, there were 676 deaths (cancer, 226; cardiovascular disease, 14

SUBMITTER: Yu Y 

PROVIDER: S-EPMC10617233 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature