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Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus Mutations, Arizona, USA.

ABSTRACT: We conducted surveillance of respiratory syncytial virus (RSV) genomic sequences for 100 RSV-A and 27 RSV-B specimens collected during November 2022-April 2023 in Arizona, USA. We identified mutations within prefusion F-protein antigenic sites in both subtypes. Continued genomic surveillance will be critical to ensure RSV vaccine effectiveness.

SUBMITTER: Holland LA

PROVIDER: S-EPMC10617361 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature

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Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus Mutations, Arizona, USA.

Holland LaRinda A LA Holland Steven C SC Smith Matthew F MF Leonard Victoria R VR Murugan Vel V Nordstrom Lora L Mulrow Mary M Salgado Raquel R White Michael M Lim Efrem S ES

Emerging infectious diseases 20230913 11

We conducted surveillance of respiratory syncytial virus (RSV) genomic sequences for 100 RSV-A and 27 RSV-B specimens collected during November 2022-April 2023 in Arizona, USA. We identified mutations within prefusion F-protein antigenic sites in both subtypes. Continued genomic surveillance will be critical to ensure RSV vaccine effectiveness. ...[more]

PMID: 37705075

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