Assessing aetiological overlap between child and adult attention-deficit hyperactivity disorder symptoms in an extended family design.

ABSTRACT:

Background

Several longitudinal studies have cast doubt on the aetiological overlap between child and adult attention-deficit hyperactivity disorder (ADHD). However, a lack of genetically sensitive data following children across adulthood precludes direct evaluation of aetiological overlap between child and adult ADHD.

Aims

We circumvent the existing gap in longitudinal data by exploring genetic overlap between maternal (adult) and offspring (child) ADHD and comorbid symptoms in an extended family cohort.

Method

Data were drawn from the Norwegian Mother, Father and Child Cohort Study, a Norwegian birth registry cohort of 114 500 children and their parents. Medical Birth Registry of Norway data were used to link extended families. Mothers self-reported their own ADHD s

SUBMITTER: Wechsler DL 

PROVIDER: S-EPMC10617499 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature