The relationship between the metabolic syndrome and arterial wall thickness: A mosaic still to be interpreted.

ABSTRACT:

Background and aims

We aimed to identify clusters of metabolic syndrome (MetS) components, risky for extremely high intima-media thickness.

Methods

We studied 41,513 volunteers (men and women) from eleven cohorts worldwide, participating in the MARE (Metabolic syndrome and Artery REsearch) Consortium.

Results

Specific clusters of MetS components - high triglycerides-high blood pressure-abdominal obesity (TBW), low HDL cholesterol-high blood pressure-abdominal obesity (HBW), high glucose-high blood pressure-abdominal obesity (GBW) - were accompanied by a 50-90% significantly greater likelihood of presenting extremely high intima-media thickness (via ultrasound of carotid artery, CCA IMT), after controlling for age, sex, smoking, non-HDL cholesterol, and presence of dia

SUBMITTER: Scuteri A 

PROVIDER: S-EPMC10617606 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature