Candidate gene-environment interactions in substance abuse: A systematic review.

ABSTRACT:

Background

The abuse of psychogenic drugs can lead to multiple health-related problems. Genetic and environmental vulnerabilities are factors in the emergence of substance use disorders. Empirical evidence regarding the gene-environment interaction in substance use is mixed. Summaries of the latest findings from a candidate gene approach will be useful for revealing the significance of particular gene contributions. Thus, we aim to identify different gene-environment interactions in patterns of substance use and investigate whether any effects trend notably across different genders and races.

Methods

We reviewed published studies, until March 1, 2022, on substance use for candidate gene-environment interaction. Basic demographics of the included studies, target genes, enviro

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC10617739 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature