Program of algorithm for pharmacological treatment of major depressive disorder in China: Benefits or not?

ABSTRACT:

Background

This research was designed to investigate Algorithm Guided Treatment (AGT) and clinical traits for the prediction of antidepressant treatment outcomes in Chinese patients with major depressive disorder (MDD).

Methods

This study included 581 patients who had reached treatment response and 406 patients remained non-responded observed after three months of treatment. Sociodemographic factors, clinical traits, and psychiatric rating scales for evaluating therapeutic responses between the two groups were compared. Logistic regression analysis was adopted to determine the risk factors of unresponsive to antidepressant (URA) in MDD. Kaplan-Meier survival analysis was utilized to compare the therapeutic response between AGT and treatment as usual (TAU).

Results

Com

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC10618797 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature