Outcomes Following Early Postoperative Adjuvant Radiosurgery for Brain Metastases.

ABSTRACT:

Importance

Adjuvant stereotactic radiosurgery (SRS) enhances the local control of resected brain metastases (BrM). However, the risks of local failure (LF) and potential for posttreatment adverse radiation effects (PTRE) after early postoperative adjuvant SRS have not yet been established.

Objective

To evaluate whether adjuvant SRS delivered within a median of 14 days after surgery is associated with improved LF without a concomitant increase in PTRE.

Design, setting, and participants

This prospective cohort study examines a clinical workflow (RapidRT) that was implemented from 2019 to 2022 to deliver SRS to surgical patients within a median of 14 days, ensuring all patients were treated within 30 days postoperatively. This prospective cohort was compared with a histo

SUBMITTER: Bander ED 

PROVIDER: S-EPMC10618851 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature