Neurodevelopment of children who are HIV-exposed and uninfected in Kenya.

ABSTRACT:

Introduction

Predictors of neurodevelopment among children who are HIV-exposed uninfected (CHEU) are poorly understood.

Methods

Mothers with and without HIV and their children were enrolled during 6-week postnatal care visits across seven sites in Kenya between March 2021 and June 2022. Infant neurodevelopment was assessed using the Malawi Developmental Assessment Tool, including social, language, fine motor and gross motor domains. We used multivariate linear mixed effects models to identify associations between 1-year neurodevelopment scores, HIV and antiretroviral therapy (ART) exposures, and household factors, adjusted for potential confounders and clustered by the site.

Results

At 1-year evaluation, CHEU (n = 709) and children who are HIV-unexposed uninfected (CH

SUBMITTER: Bulterys MA 

PROVIDER: S-EPMC10618871 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature