Spatial distribution of hand-grasp motor task activity in spinal cord functional magnetic resonance imaging.

ABSTRACT: Upper extremity motor paradigms during spinal cord functional magnetic resonance imaging (fMRI) can provide insight into the functional organization of the cord. Hand-grasping is an important daily function with clinical significance, but previous studies of similar squeezing movements have not reported consistent areas of activity and are limited by sample size and simplistic analysis methods. Here, we study spinal cord fMRI activation using a unimanual isometric hand-grasping task that is calibrated to participant maximum voluntary contraction (MVC). Two task modeling methods were considered: (1) a task regressor derived from an idealized block design (Ideal) and (2) a task regressor based on the recorded force trace normalized to individual MVC (%MVC). Across these two methods, group mo

SUBMITTER: Hemmerling KJ 

PROVIDER: S-EPMC10619382 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature