Reconstructing the somatotopic organization of the corticospinal tract remains a challenge for modern tractography methods.

ABSTRACT: The corticospinal tract (CST) is a critically important white matter fiber tract in the human brain that enables control of voluntary movements of the body. The CST exhibits a somatotopic organization, which means that the motor neurons that control specific body parts are arranged in order within the CST. Diffusion magnetic resonance imaging (MRI) tractography is increasingly used to study the anatomy of the CST. However, despite many advances in tractography algorithms over the past decade, modern, state-of-the-art methods still face challenges. In this study, we compare the performance of six widely used tractography methods for reconstructing the CST and its somatotopic organization. These methods include constrained spherical deconvolution (CSD) based probabilistic (iFOD1) and determi

SUBMITTER: He J 

PROVIDER: S-EPMC10619402 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature