A smartphone- and wearable-based biomarker for the estimation of unipolar depression severity.

ABSTRACT: Drug development for mood disorders can greatly benefit from the development of robust, reliable, and objective biomarkers. The incorporation of smartphones and wearable devices in clinical trials provide a unique opportunity to monitor behavior in a non-invasive manner. The objective of this study is to identify the correlations between remotely monitored self-reported assessments and objectively measured activities with depression severity assessments often applied in clinical trials. 30 unipolar depressed patients and 29 age- and gender-matched healthy controls were enrolled in this study. Each participant's daily physiological, physical, and social activity were monitored using a smartphone-based application (CHDR MORE™) for 3 weeks continuously. Self-reported depression anxiety stress

SUBMITTER: Zhuparris A 

PROVIDER: S-EPMC10620211 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature