Structural-functional coupling abnormalities in temporal lobe epilepsy.

ABSTRACT:

Background

Nowadays, researchers are using advanced multimodal neuroimaging techniques to construct the brain network connectome to elucidate the complex relationship among the networks of brain functions and structure. The objective of this study was to evaluate the coupling of structural connectivity (SC) and functional connectivity (FC) in the entire brain of healthy controls (HCs), and to investigate modifications in SC-FC coupling in individuals suffering from temporal lobe epilepsy (TLE).

Methods

We evaluated 65 patients with TLE matched for age and gender with 48 healthy controls. The SC-FC coupling between regions was determined, based on which whole-brain nodes were clustered. Differences in the coupling among the three groups of nodes were compared. To further vali

SUBMITTER: Huang X 

PROVIDER: S-EPMC10620528 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature