Prognostic Significance of Incipient Ulceration in Primary Cutaneous Melanoma.

ABSTRACT:

Importance

Ulceration represents a key feature in cutaneous melanoma, contributing to staging according to the current American Joint Committee on Cancer (AJCC) system. However, cases with incipient ulceration do not quite fulfill the AJCC definition of ulceration and are consequently classified as nonulcerated, presenting interpretive difficulty for pathologists. The prognostic implication of incipient ulceration is uncertain.

Objective

To evaluate the prognostic significance of incipient ulceration in cutaneous melanoma.

Design, setting, and participants

This case-control study consisted of resected primary cutaneous melanomas diagnosed between 2005 and 2015, identified from the Melanoma Institute Australia research database and with slides available for review at R

SUBMITTER: Paver EC 

PROVIDER: S-EPMC10620673 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature