Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2).

ABSTRACT:

Background

Clinicians and patients want to know the benefits and harms of outpatient treatment options for the Omicron variant of SARS-CoV-2.

Purpose

To assess the benefits and harms of 22 different COVID-19 treatments.

Data sources

The Epistemonikos COVID-19 L·OVE platform, the iSearch COVID-19 portfolio, and the World Health Organization (WHO) COVID-19 Research Database from 26 November 2021 to 2 March 2023.

Study selection

Two reviewers independently screened abstracts and full texts against a priori-defined criteria.

Data extraction

One reviewer extracted the data and assessed the risk of bias and certainty of evidence (COE). A second reviewer verified the data abstraction and assessments.

Data synthesis

Two randomized controlled trials and 6

SUBMITTER: Sommer I 

PROVIDER: S-EPMC10620953 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature