The association between hypertensive angiopathy and cerebral amyloid angiopathy in primary intracerebral hemorrhage.

ABSTRACT:

Objective

To determine the association between the burden of cerebral small vessel disease (CSVD) due to hypertensive angiopathy (HA) and cerebral amyloid angiopathy (CAA) on MRI in patients with primary intracerebral hemorrhage (ICH).

Methods

Patients with primary ICH admitted to our center from March 2012 to November 2021 were consecutively enrolled. We used multivariate binary and ordinal regression analyses to assess the association between HA-CSVD burden and CAA-CSVD burden. Lobar cerebral microbleeds (CMBs) were categorized into three level of severity: 0-1, 2-4, and ≥ 5 lobar CMBs. A high CAA-CSVD score was defined as a CAA-CSVD score of ≥3.

Results

Overall, 222 participants (mean age 59.88 ± 13.56) were included into analysis. Age and ICH etiology differed amo

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC10621040 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature