AI-based AlphaFold2 significantly expands the structural space of the autophagy pathway.

ABSTRACT:

Abbreviations

AF2: AlphaFold2; AF2-Mult: AlphaFold2 multimer; ATG: autophagy-related; CTD: C-terminal domain; ECTD: extreme C-terminal domain; FR: flexible region; MD: molecular dynamics; NTD: N-terminal domain; pLDDT: predicted local distance difference test; UBL: ubiquitin-like.

SUBMITTER: Malhotra N 

PROVIDER: S-EPMC10621275 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature