Association between psoriasis and serum apolipoprotein A1 and B: A systematic review and meta-analysis.

ABSTRACT:

Background

Psoriasis has been linked to dyslipidemia. However, the magnitude of the association between psoriasis and serum apolipoproteins A1 and B remains unclear.

Methods

We systematically searched PubMed, Embase, and Cochrane Library databases for eligible studies published before August 10, 2023. Data were pooled using Stata software. We adopted a random-effects model for the meta-analysis. Additionally, we conducted subgroup analyses of the studies according to the psoriasis type and matched body mass index (BMI).

Results

Seventeen studies involving 2467 participants were included. Psoriasis was associated with decreased serum apolipoprotein A1 (weighted mean difference [WMD] = -9.05, P < 0.001) and increased serum apolipoprotein B (WMD = 11.68, P 

SUBMITTER: Wang F 

PROVIDER: S-EPMC10622706 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature